Bus routes from Santiago to Santa Cruz
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What to expect of your trip
Fast, easy, and affordable options from Santiago to Santa Cruz
Avg. trip duration
2 hr 40 mins
Avg. distance
190 km
Cheapest trip
From $11.98
13
Avg. trips a day
On this page
Bus stations and stops in Santiago
Santiago (Terminal San Borja)
Francisco de Borja
Estación Central, Región Metropolitana
122 Santiago
Chile
Estación Central, Región Metropolitana
122 Santiago
Chile
View this address on Google Maps
Departures South, San Antonio And Quintero : Platforms 30 to 43 |
Departures North: Platforms 30 to 43 |
Departures V Region Vina del mar y ValparaisoPlatforms: 30 to 43 |
Please arrive before the time marked on your ticket to avoid missing your trip.
Santiago (Pajaritos)
Avenida General Óscar Bonilla altura 5600
Estación Metro Pajaritos
8980000 Santiago
Chile
Estación Metro Pajaritos
8980000 Santiago
Chile
Santiago (Los Libertadores)
Av. Américo Vespucio, Quilicura
8710083 Santiago
Chile
8710083 Santiago
Chile
View this address on Google Maps
Departures Platform 16
Santiago (Terminal Del Sol)
Cruce Colón
San Bernardo, Santiago Metropolitan Region, Chile
8071042 Santiago
Chile
8071042 Santiago
Chile
View this address on Google Maps
Colon Crossing stop in San Bernardo
Santiago (Terminal Sur)
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Frequently asked questions
Where can I see if my bus from Santiago to Santa Cruz is on time?
How long does it take from Santiago to Santa Cruz by bus?
What is the distance between Santiago and Santa Cruz?
How much is the bus ticket between Santiago and Santa Cruz?
How can I pay for the bus from Santiago to Santa Cruz?
When is the cheapest time to book a bus ticket from Santiago to Santa Cruz?
Buses from Santiago to Santa Cruz
Find the cheapest buses from Santiago to Santa Cruz
It couldn’t be easier to book your travel from Santiago to Santa Cruz with FlixBus - and when you book in advance, you can save money too!
FlixBus operates in 46 countries connecting 5000 destinations. So no matter where you want to go, we can take you there!
Ticket prices cost as little as $11.98.To get the cheapest tickets, book online in advance and avoid busy times like weekends and public holidays.
The distance between Santiago and Santa Cruz is 190 km, which takes as little as 2 hours 40 minutes with our fastest rides.
Make your journey even easier with the FlixBus app. All your information will be saved for the next time you travel.
Traveling from Santiago to Santa Cruz
No matter whether you want to travel first thing in the morning or late at night, you’ll find a journey to suit you with 14 ridesbetween Santiago and Santa Cruz.
The first bus is at 6:15 am with the last bus leaving at 8:59 pm. The rides from Santiago to Santa Cruz take a minimum of 2 hours 40 minutes; what’s more, when you travel by bus, you don’t need to worry about traffic or delays en route. Just relax and enjoy the journey with free WiFi and plenty of legroom.
You can pick up a bus ticket for just $11.98 - that’s way cheaper than traveling by any other method.
Buses are also a great choice for environmentally-conscious travelers. We’re working towards being 100% carbon neutral and offer all travelers the opportunity to offset their carbon emissions when booking their tickets. Simply select the “CO2 compensation" box when paying online and we’ll use all of the money to make a direct impact on the future of sustainable mobility.
Taking the bus from Santiago
Ready for your journey from Santiago?
Santiago has 6 stations and is well connected with buses to 48 destinations across the country.
No matter where you’re traveling from, you can find plenty of information on our website or by contacting FlixBus directly for travel information. We’ll do our best to make sure you’re well-equipped for your journey, so you can experience everything the trip has to offer.
Arrival in Santa Cruz
Start planning your trip to Santa Cruz now. Never visited before? Here’s all you need to know.
Santa Cruz is one of the best-connected cities, so you’re not short on choices of how to get here.
FlixBus has one bus stop in Santa Cruz, connecting 4 cities.
Never miss a beat as you sample the sights and culture synonymous with this city. Now is the time to hop aboard FlixBus and explore!
What to expect onboard the FlixBus bus from Santiago to Santa Cruz
Traveling from Santiago to Santa Cruz is quick, clean and comfortable - and it couldn’t be easier to book a ticket. You can book online via the website, on our app, in person at a FlixShop or using Google Assistant.
We accept card payment as well as Paypal, Google Pay, and Apple Pay, but there are many more payment options that you can choose from.
The easiest way to book your ticket is using our app. You’ll be able to make your reservation within seconds and there’s no need to print and carry the ticket with you, as your phone will be your ticket.
Want to sit beside family or friends or keep the space beside you free? Need easy access to the toilet or a table to get on with some work whilst traveling? You can reserve a seat when you book on the app or website, and you can choose from a variety of seat options including a table seat, panorama seat or extra seat.
Once you’re settled in your seat, you can sit back and relax with plenty of onboard services to help you make the most of your trip. Most of our buses have onboard Wifi and an entertainment system so you can catch up on your favorite shows or listen to audiobooks. We’ve also got toilets onboard, as well as power outlets.
What’s more, you get a generous luggage allowance when you travel with FlixBus with one carry-on bag and one checked bag, so you can bring everything you need for your trip.
Discover more popular bus connections
- Santiago - Viña del Mar
- Viña del Mar - Santiago
- Santiago - La Serena
- Santiago - Valparaíso
- La Serena - Santiago
- Valparaíso - Santiago
- Santiago - Puerto Montt
- Santiago - Valdivia
- Valdivia - Santiago
- Santiago - San Antonio
- San Antonio - Santiago
- Puerto Montt - Santiago
- Santiago - Santa Cruz
- Santa Cruz - Santiago
Onboard services are subject to availability